Genomic analysis of Klebsiella pneumoniae isolates from Malawi reveals acquisition of multiple ESBL determinants across diverse lineages | Zendy

Patrick Musicha | Zendy; Chisomo Msefula | Zendy; Alison E. Mather | Zendy; Chrispin Chaguza | Zendy; Amy K. Cain | Zendy; Chikondi Peno | Zendy; Teemu Kallonen | Zendy; Margaret Khonga | Zendy; Brigitte Denis | Zendy; Katherine J. Gray | Zendy; Robert S. Heyderman | Zendy; Nicholas R. Thomson | Zendy; Dean Everett | Zendy; Nicholas Feasey | Zendy

Open Access

Genomic analysis of Klebsiella pneumoniae isolates from Malawi reveals acquisition of multiple ESBL determinants across diverse lineages

Author(s) -

Patrick Musicha,

Chisomo Msefula,

Alison E. Mather,

Chrispin Chaguza,

Amy K. Cain,

Chikondi Peno,

Teemu Kallonen,

Margaret Khonga,

Brigitte Denis,

Katherine J. Gray,

Robert S. Heyderman,

Nicholas R. Thomson,

Dean Everett,

Nicholas Feasey

Publication year - 2019

Publication title -

journal of antimicrobial chemotherapy

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.124

H-Index - 194

eISSN - 1460-2091

pISSN - 0305-7453

DOI - 10.1093/jac/dkz032

Subject(s) - biology , klebsiella pneumoniae , population , context (archaeology) , plasmid , antibiotic resistance , phylogenetic tree , carbapenem , microbiology and biotechnology , genetics , gene , antibiotics , escherichia coli , medicine , environmental health , paleontology

ESBL-producing Klebsiella pneumoniae (KPN) pose a major threat to human health globally. We carried out a WGS study to understand the genetic background of ESBL-producing KPN in Malawi and place them in the context of other global isolates.

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