Open AccessTolerability of long-term fluconazole therapy
Author(s) -
Matthew R Davis,
Minh-Vu H Nguyen,
Monica Donnelley,
George R. Thompson
Publication year - 2018
Publication title -
journal of antimicrobial chemotherapy
Language(s) - Uncategorized
Resource type - Journals
SCImago Journal Rank - 2.124
H-Index - 194
eISSN - 1460-2091
pISSN - 0305-7453
DOI - 10.1093/jac/dky501
Subject(s) - fluconazole , adverse effect , tolerability , medicine , discontinuation , regimen , antifungal , dermatology
Fluconazole is a commonly prescribed first-generation triazole antifungal. Although the toxicity profile of fluconazole has been evaluated in clinical trials, there are scant data regarding its tolerability with long-term therapy. Treatment guidelines for coccidioidomycosis recommend fluconazole therapy and severe or disseminated infections can require lifelong treatment.
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