Open AccessIntra-individual effects of food upon the pharmacokinetics of rifampicin and isoniazid
Author(s) -
Ana RequenaMéndez,
Geraint Davies,
David Waterhouse,
Alison Ardrey,
Oswaldo Jave,
Sonia Llanet López-Romero,
Stephen A. Ward,
David Moore
Publication year - 2018
Publication title -
journal of antimicrobial chemotherapy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.124
H-Index - 194
eISSN - 1460-2091
pISSN - 0305-7453
DOI - 10.1093/jac/dky444
Subject(s) - isoniazid , rifampicin , cmax , pharmacokinetics , medicine , pharmacology , drug , gastroenterology , tuberculosis , pathology
Poor response to TB therapy might be attributable to subtherapeutic levels in drug-compliant patients. Pharmacokinetic parameters can be affected by comorbidities or the interaction of drugs with food.
Accelerating Research
Robert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom
Address
John Eccles HouseRobert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom