Evaluation of multiplex tandem PCR (MT-PCR) assays for the detection of bacterial resistance genes among Enterobacteriaceae in clinical urines | Zendy

Katrin Schmidt | Zendy; Keith K. Stanley | Zendy; Richard Hale | Zendy; L. M. Smith | Zendy; John Wain | Zendy; Justin O’Grady | Zendy; David M. Livermore | Zendy

Open Access

Evaluation of multiplex tandem PCR (MT-PCR) assays for the detection of bacterial resistance genes among Enterobacteriaceae in clinical urines

Author(s) -

Katrin Schmidt,

Keith K. Stanley,

Richard Hale,

L. M. Smith,

John Wain,

Justin O’Grady,

David M. Livermore

Publication year - 2018

Publication title -

journal of antimicrobial chemotherapy

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.124

H-Index - 194

eISSN - 1460-2091

pISSN - 0305-7453

DOI - 10.1093/jac/dky419

Subject(s) - biology , microbiology and biotechnology , bacteria , escherichia coli , multiplex , multiplex polymerase chain reaction , antibiotic resistance , enterobacteriaceae , polymerase chain reaction , antibiotics , gene , genetics

Increasing resistance drives empirical use of less potent and previously reserved antibiotics, including for urinary tract infections (UTIs). Molecular profiling, without culture, might better guide early therapy.

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