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Quantifying the contribution of four resistance mechanisms to ciprofloxacin MIC inEscherichia coli: a systematic review
Author(s) -
Boas C.L. van der Putten,
Daniel Remondini,
Giovanni Pasquini,
Victoria A. Janes,
Sébastien Matamoros,
Constance Schultsz
Publication year - 2018
Publication title -
journal of antimicrobial chemotherapy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.124
H-Index - 194
eISSN - 1460-2091
pISSN - 0305-7453
DOI - 10.1093/jac/dky417
Subject(s) - ciprofloxacin , escherichia coli , biology , microbiology and biotechnology , genetics , efflux , genotype , antibiotic resistance , drug resistance , gene , bacteria
Reviews assessing the genetic basis of ciprofloxacin resistance in Escherichia coli have mostly been qualitative. However, to predict resistance phenotypes based on genotypic characteristics, it is essential to quantify the contribution of genotypic determinants to resistance.

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