Clostridioides difficileincidence related to in-hospital cephalosporin use: a tale of two highly comparable hospitals | Zendy

Johan Karp | Zendy; Jon Edman-Wallér | Zendy; Michael Toepfer | Zendy; Anders Lundqvist | Zendy; Gunnar Jacobsson | Zendy

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Clostridioides difficileincidence related to in-hospital cephalosporin use: a tale of two highly comparable hospitals

Author(s) -

Johan Karp,

Jon Edman-Wallér,

Michael Toepfer,

Anders Lundqvist,

Gunnar Jacobsson

Publication year - 2018

Publication title -

journal of antimicrobial chemotherapy

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.124

H-Index - 194

eISSN - 1460-2091

pISSN - 0305-7453

DOI - 10.1093/jac/dky408

Subject(s) - medicine , cephalosporin , incidence (geometry) , antibiotics , clostridium difficile , piperacillin , tazobactam , defined daily dose , clostridioides , antibiotic stewardship , antimicrobial stewardship , piperacillin/tazobactam , emergency medicine , intensive care medicine , pediatrics , antibiotic resistance , microbiology and biotechnology , pharmacology , imipenem , medical prescription , bacteria , biology , physics , genetics , optics , pseudomonas aeruginosa

Antibiotic treatment is a well-known risk factor for healthcare facility-associated Clostridioides (Clostridium) difficile infection (HCF-CDI). Antibiotic stewardship programmes (ASPs) targeting high-risk antibiotics have been shown to decrease HCF-CDI incidence. HCF-CDI incidence is high in Nordic countries despite relatively low antibiotic use in hospital.

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