Adjunctive protein synthesis inhibitor antibiotics for toxin suppression in Staphylococcus aureus infections: a systematic appraisal
Author(s) -
Anita Campbell,
Ravindra Dotel,
Christopher C. Blyth,
Joshua S. Davis,
Steven Y. C. Tong,
Asha C Bowen
Publication year - 2018
Publication title -
journal of antimicrobial chemotherapy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.124
H-Index - 194
eISSN - 1460-2091
pISSN - 0305-7453
DOI - 10.1093/jac/dky387
Subject(s) - staphylococcus aureus , antibiotics , microbiology and biotechnology , toxin , virulence , protein synthesis inhibitor , micrococcaceae , staphylococcal infections , virulence factor , antibacterial agent , medicine , biology , bacteria , biochemistry , genetics , gene
Protein synthesis inhibitor antibiotics inhibit synthesis of new proteins, including exotoxins and other important virulence determinants in Staphylococcus aureus. A summary of the literature regarding the use of adjunctive protein synthesis inhibitors for toxin suppression in the setting of S. aureus infections is presented.
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