High efavirenz serum concentrations in TB/HIV-coinfected Ugandan adults with a CYP2B6 516 TT genotype on anti-TB treatment | Zendy

Amrei von Braun | Zendy; Barbara Castelnuovo | Zendy; Bruno Ledergerber | Zendy; Jessica Cusato | Zendy; Allan Buzibye | Zendy; Andrew Kambugu | Zendy; Jan Fehr | Zendy; Andrea Calcagno | Zendy; Mohammed Lamorde | Zendy; Christine SekaggyaWiltshire | Zendy

Open Access

High efavirenz serum concentrations in TB/HIV-coinfected Ugandan adults with a CYP2B6 516 TT genotype on anti-TB treatment

Author(s) -

Amrei von Braun,

Barbara Castelnuovo,

Bruno Ledergerber,

Jessica Cusato,

Allan Buzibye,

Andrew Kambugu,

Jan Fehr,

Andrea Calcagno,

Mohammed Lamorde,

Christine SekaggyaWiltshire

Publication year - 2018

Publication title -

journal of antimicrobial chemotherapy

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.124

H-Index - 194

eISSN - 1460-2091

pISSN - 0305-7453

DOI - 10.1093/jac/dky379

Subject(s) - efavirenz , genotype , medicine , human immunodeficiency virus (hiv) , coinfection , virology , cyp2b6 , antiretroviral therapy , biology , viral load , cyp3a4 , genetics , cytochrome p450 , metabolism , gene

To report the efavirenz serum concentrations in TB/HIV-coinfected Ugandan adults on concomitant anti-TB treatment and analyse factors associated with elevated concentrations in this specific population.

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