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Activity of hypothiocyanite and lactoferrin (ALX-009) against respiratory cystic fibrosis pathogens in sputum
Author(s) -
Michael M. Tunney,
J. Payne,
Stephanie McGrath,
G.G. Einarsson,
Rebecca J. Ingram,
D.F. Gilpin,
V. Juarez-Perez,
J.S. Elborn
Publication year - 2018
Publication title -
journal of antimicrobial chemotherapy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.124
H-Index - 194
eISSN - 1460-2091
pISSN - 0305-7453
DOI - 10.1093/jac/dky357
Subject(s) - sputum , pseudomonas aeruginosa , tobramycin , microbiology and biotechnology , cystic fibrosis , antimicrobial , antibiotics , medicine , chemistry , biology , bacteria , gentamicin , pathology , tuberculosis , genetics
To determine the antimicrobial activity of ALX-009, a combination of bovine lactoferrin and hypothiocyanite, in sputum against Pseudomonas aeruginosa and Burkholderia cepacia complex (Bcc), key pathogens causing infection in the lungs of cystic fibrosis (CF) patients.

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