High prevalence of virological failure and HIV drug mutations in a first-line cohort of Malawian children | Zendy

Minke H. W. Huibers | Zendy; Pieter Moons | Zendy; Marion Cornelissen | Zendy; Fokla Zorgdrager | Zendy; Nombulelo Maseko | Zendy; Montfort Bernard Gushu | Zendy; Oluwadamilola H. Iwajomo | Zendy; Michaël Boele van Hensbroek | Zendy; Job C. J. Calis | Zendy

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High prevalence of virological failure and HIV drug mutations in a first-line cohort of Malawian children

Author(s) -

Minke H. W. Huibers,

Pieter Moons,

Marion Cornelissen,

Fokla Zorgdrager,

Nombulelo Maseko,

Montfort Bernard Gushu,

Oluwadamilola H. Iwajomo,

Michaël Boele van Hensbroek,

Job C. J. Calis

Publication year - 2018

Publication title -

journal of antimicrobial chemotherapy

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.124

H-Index - 194

eISSN - 1460-2091

pISSN - 0305-7453

DOI - 10.1093/jac/dky348

Subject(s) - medicine , nevirapine , viral load , drug resistance , population , cohort , regimen , prospective cohort study , virology , genotype , human immunodeficiency virus (hiv) , immunology , antiretroviral therapy , environmental health , biology , genetics , gene

Drug resistance mutations (DRMs) increasingly jeopardize paediatric HIV programmes in sub-Saharan Africa. As individual monitoring of DRMs and viral loads has limited availability, population data on DRMs are essential to determine first-line susceptibility. Paediatric data from sub-Saharan Africa are scarce and unavailable for Malawi.

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