Variability of ciprofloxacin pharmacokinetics in children: impact on dose range in sickle cell patients | Zendy

A. Facchin | Zendy; S. Bui | Zendy; Stéphanie Leroux | Zendy; Fabienne Nacka | Zendy; Bérengère Koehl | Zendy; Esraa G.A. El Maksoud | Zendy; Michaël Fayon | Zendy; Evelyne JacqzAigrain | Zendy

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Variability of ciprofloxacin pharmacokinetics in children: impact on dose range in sickle cell patients

Author(s) -

A. Facchin,

S. Bui,

Stéphanie Leroux,

Fabienne Nacka,

Bérengère Koehl,

Esraa G.A. El Maksoud,

Michaël Fayon,

Evelyne JacqzAigrain

Publication year - 2018

Publication title -

journal of antimicrobial chemotherapy

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.124

H-Index - 194

eISSN - 1460-2091

pISSN - 0305-7453

DOI - 10.1093/jac/dky328

Subject(s) - pharmacokinetics , ciprofloxacin , nonmem , medicine , dosing , population , volume of distribution , renal function , antibacterial agent , gastroenterology , cystic fibrosis , pharmacology , antibiotics , biology , microbiology and biotechnology , environmental health

To determine the ciprofloxacin population pharmacokinetics in paediatric patients and the impact of underlying disease and evaluate the appropriateness of current dosage regimens.

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