Effects of prophylactic antibiotics on patients with stable COPD: a systematic review and meta-analysis of randomized controlled trials
Author(s) -
Yuanyuan Wang,
Tanja R. Zijp,
Muh. Akbar Bahar,
Janwillem Kocks,
Bob Wilffert,
Eelko Hak
Publication year - 2018
Publication title -
journal of antimicrobial chemotherapy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.124
H-Index - 194
eISSN - 1460-2091
pISSN - 0305-7453
DOI - 10.1093/jac/dky326
Subject(s) - medicine , antibiotics , exacerbation , copd , randomized controlled trial , azithromycin , relative risk , adverse effect , meta analysis , erythromycin , intensive care medicine , confidence interval , microbiology and biotechnology , biology
As bacterial infections provoke exacerbations, COPD patients may benefit from prophylactic antibiotics. However, evidence regarding their overall benefit-risk profile is conflicting.
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