Impact of OqxR loss of function on the envelope proteome of Klebsiella pneumoniae and susceptibility to antimicrobials
Author(s) -
Wan Ahmad Kamil Wan Nur Ismah,
Yuiko Takebayashi,
Jacqueline Findlay,
Kate J. Heesom,
Matthew B. Avison
Publication year - 2018
Publication title -
journal of antimicrobial chemotherapy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.124
H-Index - 194
eISSN - 1460-2091
pISSN - 0305-7453
DOI - 10.1093/jac/dky293
Subject(s) - klebsiella pneumoniae , antimicrobial , microbiology and biotechnology , envelope (radar) , proteome , klebsiella , biology , medicine , escherichia coli , bioinformatics , genetics , computer science , gene , telecommunications , radar
In Klebsiella pneumoniae, loss-of-function mutations in the transcriptional repressors RamR and OqxR both have an impact on the production of efflux pumps and porins relevant to antimicrobial efflux/entry.
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