Drug resistance outcomes of long-term ART with tenofovir disoproxil fumarate in the absence of virological monitoring | Zendy

Giovanni Carlo Federico Villa | Zendy; Richard Odame Phillips | Zendy; Colette Smith | Zendy; Alexander Stockdale | Zendy; Alessandra Ruggiero | Zendy; Apostolos Beloukas | Zendy; Lambert Appiah | Zendy; David Chadwick | Zendy; Fred Stephen Sarfo | Zendy; Anna María Geretti | Zendy

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Drug resistance outcomes of long-term ART with tenofovir disoproxil fumarate in the absence of virological monitoring

Author(s) -

Giovanni Carlo Federico Villa,

Richard Odame Phillips,

Colette Smith,

Alexander Stockdale,

Alessandra Ruggiero,

Apostolos Beloukas,

Lambert Appiah,

David Chadwick,

Fred Stephen Sarfo,

Anna María Geretti

Publication year - 2018

Publication title -

journal of antimicrobial chemotherapy

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.124

H-Index - 194

eISSN - 1460-2091

pISSN - 0305-7453

DOI - 10.1093/jac/dky281

Subject(s) - efavirenz , lamivudine , stavudine , zidovudine , virology , resistance mutation , viral load , emtricitabine , ritonavir , lopinavir , drug resistance , cobicistat , medicine , reverse transcriptase inhibitor , pharmacology , biology , virus , viral disease , antiretroviral therapy , microbiology and biotechnology , reverse transcriptase , polymerase chain reaction , hepatitis b virus , biochemistry , gene

The resistance profiles of patients receiving long-term ART in sub-Saharan Africa have been poorly described. This study obtained a sensitive assessment of the resistance patterns associated with long-term tenofovir-based ART in a programmatic setting where virological monitoring is yet to become part of routine care.

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