Resolution of dynamic MDR structures among the plasmidome of Salmonella using MinION single-molecule, long-read sequencing | Zendy

Ruichao Li | Zendy; Kaichao Chen | Zendy; Edward WaiChi Chan | Zendy; Sheng Chen | Zendy

Open Access

Resolution of dynamic MDR structures among the plasmidome of Salmonella using MinION single-molecule, long-read sequencing

Author(s) -

Ruichao Li,

Kaichao Chen,

Edward WaiChi Chan,

Sheng Chen

Publication year - 2018

Publication title -

journal of antimicrobial chemotherapy

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.124

H-Index - 194

eISSN - 1460-2091

pISSN - 0305-7453

DOI - 10.1093/jac/dky243

Subject(s) - minion , salmonella , resolution (logic) , microbiology and biotechnology , computational biology , biology , nanopore sequencing , computer science , genetics , dna sequencing , bacteria , dna , artificial intelligence

ISCR1 is an important mobile genetic element mediating the transfer of antibiotic resistance genes. Genetic diversity regarding distribution and copy numbers of ISCR1 within a bacterial population derived from an ancestral strain, which may reflect the degree of genetic plasticity conferred by such an element, has not been studied.

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