Pharmacokinetics of intravenous and nebulized gentamicin in critically ill patients | Zendy

Matthieu Boisson | Zendy; Olivier Mimoz | Zendy; Mirza Hadzic | Zendy; Sandrine Marchand | Zendy; Christophe Adier | Zendy; William Couet | Zendy; Nicolas Grégoire | Zendy

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Pharmacokinetics of intravenous and nebulized gentamicin in critically ill patients

Author(s) -

Matthieu Boisson,

Olivier Mimoz,

Mirza Hadzic,

Sandrine Marchand,

Christophe Adier,

William Couet,

Nicolas Grégoire

Publication year - 2018

Publication title -

journal of antimicrobial chemotherapy

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.124

H-Index - 194

eISSN - 1460-2091

pISSN - 0305-7453

DOI - 10.1093/jac/dky239

Subject(s) - gentamicin , medicine , pharmacokinetics , bronchoalveolar lavage , dosing , aminoglycoside , anesthesia , pneumonia , bioavailability , population , antibiotics , pharmacology , lung , chemistry , biochemistry , environmental health

Optimal dosing for nebulized gentamicin is unknown. We compared the pulmonary and systemic pharmacokinetics (PK) of gentamicin following intravenous and nebulized administration in mechanically ventilated patients.

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