Impact of transmitted HIV-1 drug resistance on the efficacy of first-line antiretroviral therapy with two nucleos(t)ide reverse transcriptase inhibitors plus an integrase inhibitor or a protease inhibitor
Author(s) -
Chiara Spertilli Raffaelli,
Barbara Rossetti,
Lorenzo Paglicci,
Manuela Colafigli,
Grazia Punzi,
Vanni Borghi,
Monica Pecorari,
Maria Mercedes Santoro,
Giovanni Penco,
Andrea Antinori,
Maurizio Zazzi,
Andrea De Luca,
Giacomo Zanelli
Publication year - 2018
Publication title -
journal of antimicrobial chemotherapy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.124
H-Index - 194
eISSN - 1460-2091
pISSN - 0305-7453
DOI - 10.1093/jac/dky211
Subject(s) - integrase , hazard ratio , drug resistance , medicine , hiv drug resistance , integrase inhibitor , viral load , virology , gastroenterology , human immunodeficiency virus (hiv) , pharmacology , antiretroviral therapy , biology , confidence interval , microbiology and biotechnology
To examine the impact of transmitted drug resistance (TDR) on response to first-line regimens with integrase strand transfer inhibitors (INSTIs) or boosted protease inhibitors (bPIs).
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