Complete genomic characterization of two Escherichia coli lineages responsible for a cluster of carbapenem-resistant infections in a Chinese hospital | Zendy

Zhiyong Zong | Zendy; Samuel Fenn | Zendy; Christopher Connor | Zendy; Yu Feng | Zendy; Alan McNally | Zendy

Open Access

Complete genomic characterization of two Escherichia coli lineages responsible for a cluster of carbapenem-resistant infections in a Chinese hospital

Author(s) -

Zhiyong Zong,

Samuel Fenn,

Christopher Connor,

Yu Feng,

Alan McNally

Publication year - 2018

Publication title -

journal of antimicrobial chemotherapy

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.124

H-Index - 194

eISSN - 1460-2091

pISSN - 0305-7453

DOI - 10.1093/jac/dky210

Subject(s) - escherichia coli , carbapenem , microbiology and biotechnology , biology , enterobacteriaceae , cluster (spacecraft) , genetics , antibiotics , gene , computer science , programming language

The increase in infections as a result of MDR strains of Escherichia coli is a global health crisis. The emergence of globally disseminated lineages of E. coli carrying ESBL genes has been well characterized. An increase in strains producing carbapenemase enzymes and mobile colistin resistance is now being reported, but to date there is little genomic characterization of such strains.

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