Pharmacokinetics of rifampicin in adult TB patients and healthy volunteers: a systematic review and meta-analysis | Zendy

Katharine E. Stott | Zendy; Henry Pertinez | Zendy; Marieke G. G. Sturkenboom | Zendy; Martin J. Boeree | Zendy; Rob E. Aarnoutse | Zendy; Geetha Ramachandran | Zendy; Ana RequenaMéndez | Zendy; Charles A. Peloquin | Zendy; Coenraad F.N. Koegelenberg | Zendy; JanWillem C. Alffenaar | Zendy; Rovina Ruslami | Zendy; Alma Tostmann | Zendy; Soumya Swaminathan | Zendy; Helen McIlleron | Zendy; Geraint Davies | Zendy

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Pharmacokinetics of rifampicin in adult TB patients and healthy volunteers: a systematic review and meta-analysis

Author(s) -

Katharine E. Stott,

Henry Pertinez,

Marieke G. G. Sturkenboom,

Martin J. Boeree,

Rob E. Aarnoutse,

Geetha Ramachandran,

Ana RequenaMéndez,

Charles A. Peloquin,

Coenraad F.N. Koegelenberg,

JanWillem C. Alffenaar,

Rovina Ruslami,

Alma Tostmann,

Soumya Swaminathan,

Helen McIlleron,

Geraint Davies

Publication year - 2018

Publication title -

journal of antimicrobial chemotherapy

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.124

H-Index - 194

eISSN - 1460-2091

pISSN - 0305-7453

DOI - 10.1093/jac/dky152

Subject(s) - medicine , pharmacokinetics , rifampicin , meta analysis , pharmacology , tuberculosis , antibacterial agent , intensive care medicine , antibiotics , pathology , microbiology and biotechnology , biology

The objectives of this study were to explore inter-study heterogeneity in the pharmacokinetics (PK) of orally administered rifampicin, to derive summary estimates of rifampicin PK parameters at standard dosages and to compare these with summary estimates for higher dosages.

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