Prevalence and characterization of azole-resistant Aspergillus fumigatus in patients with cystic fibrosis: a prospective multicentre study in Germany | Zendy

R. Seufert | Zendy; Ludwig Sedlacek | Zendy; Barbara C. Kahl | Zendy; Michael Hogardt | Zendy; Axel Hamprecht | Zendy; Gerhard Haase | Zendy; Florian Gunzer | Zendy; A. Haas | Zendy; Silke Grauling-Halama | Zendy; Colin R. MacKenzie | Zendy; A. Essig | Zendy; Florian Stehling | Zendy; Sivagurunathan Sutharsan | Zendy; S. Dittmer | Zendy; David Killengray | Zendy; Dirk Schmidt | Zendy; Narges Eskandarian | Zendy; Eike Steinmann | Zendy; Jan Buer | Zendy; Ferry Hagen | Zendy; Jacques F. Meis | Zendy; P.M. Rath | Zendy; Jörg Steinmann | Zendy

Open Access

Prevalence and characterization of azole-resistant Aspergillus fumigatus in patients with cystic fibrosis: a prospective multicentre study in Germany

Author(s) -

R. Seufert,

Ludwig Sedlacek,

Barbara C. Kahl,

Michael Hogardt,

Axel Hamprecht,

Gerhard Haase,

Florian Gunzer,

A. Haas,

Silke Grauling-Halama,

Colin R. MacKenzie,

A. Essig,

Florian Stehling,

Sivagurunathan Sutharsan,

S. Dittmer,

David Killengray,

Dirk Schmidt,

Narges Eskandarian,

Eike Steinmann,

Jan Buer,

Ferry Hagen,

Jacques F. Meis,

P.M. Rath,

Jörg Steinmann

Publication year - 2018

Publication title -

journal of antimicrobial chemotherapy

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.124

H-Index - 194

eISSN - 1460-2091

pISSN - 0305-7453

DOI - 10.1093/jac/dky147

Subject(s) - aspergillus fumigatus , genotyping , azole , microbiology and biotechnology , broth microdilution , cystic fibrosis , biology , genotype , medicine , antibiotics , antifungal , minimum inhibitory concentration , gene , genetics

Aspergillus fumigatus is the most prevalent filamentous fungus in the respiratory tract of patients with cystic fibrosis (CF). The aim of this prospective multicentre study was to investigate the prevalence of azole-resistant A. fumigatus (ARAF) in respiratory secretions from CF patients across Germany and to characterize ARAF isolates by phenotypic and molecular methods.

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