Plasma and CSF pharmacokinetics of meropenem in neonates and young infants: results from the NeoMero studies | Zendy

Eva Germovsek | Zendy; Irja Lutsar | Zendy; Karin Kipper | Zendy; Mats O. Karlsson | Zendy; Tim Planche | Zendy; Corine Chazallon | Zendy; Laurence Meyer | Zendy; Ursula Trafojer | Zendy; Tuuli Metsvaht | Zendy; Isabelle Fournier | Zendy; Mike Sharland | Zendy; Paul T. Heath | Zendy; Joseph F. Standing | Zendy; Cinzia Auriti | Zendy; Susanna Esposito | Zendy; Pugini Lorenza | Zendy; MariLiis Ilmoja | Zendy; Nijolė Drazdienė | Zendy; Kosmas Sarafidis | Zendy; Georgıos Mitsiakos | Zendy; Michiel van der Flier | Zendy; Paul Clarke | Zendy; Andrew Collinson | Zendy; Samir Gupta | Zendy; Mark Anthony | Zendy; Mark Thomas | Zendy; Santosh Pattnayak | Zendy; Jonathan Davis | Zendy; Heike Rabe | Zendy; Elizabeth A. Pilling | Zendy; Srini Bandi | Zendy; Ajay Sinha | Zendy

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Plasma and CSF pharmacokinetics of meropenem in neonates and young infants: results from the NeoMero studies

Author(s) -

Eva Germovsek,

Irja Lutsar,

Karin Kipper,

Mats O. Karlsson,

Tim Planche,

Corine Chazallon,

Laurence Meyer,

Ursula Trafojer,

Tuuli Metsvaht,

Isabelle Fournier,

Mike Sharland,

Paul T. Heath,

Joseph F. Standing,

Cinzia Auriti,

Susanna Esposito,

Pugini Lorenza,

MariLiis Ilmoja,

Nijolė Drazdienė,

Kosmas Sarafidis,

Georgıos Mitsiakos,

Michiel van der Flier,

Paul Clarke,

Andrew Collinson,

Samir Gupta,

Mark Anthony,

Mark Thomas,

Santosh Pattnayak,

Jonathan Davis,

Heike Rabe,

Elizabeth A. Pilling,

Srini Bandi,

Ajay Sinha

Publication year - 2018

Publication title -

journal of antimicrobial chemotherapy

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.124

H-Index - 194

eISSN - 1460-2091

pISSN - 0305-7453

DOI - 10.1093/jac/dky128

Subject(s) - meropenem , pharmacokinetics , medicine , pharmacology , microbiology and biotechnology , antibiotics , biology , antibiotic resistance

Sepsis and bacterial meningitis are major causes of mortality and morbidity in neonates and infants. Meropenem, a broad-spectrum antibiotic, is not licensed for use in neonates and infants below 3 months of age and sufficient information on its plasma and CSF disposition and dosing in neonates and infants is lacking.

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