Low prevalence of transmitted HIV-1 drug resistance detected by a dried blood spot (DBS)-based next-generation sequencing (NGS) method in newly diagnosed individuals in Cameroon in the years 2015–16 | Zendy

Herbert A Mbunkah | Zendy; Alex Marzel | Zendy; Stefan Schmutz | Zendy; Yik Lim Kok | Zendy; Osvaldo Zagordi | Zendy; Mohaned Shilaih | Zendy; Ndi N Nsanwe | Zendy; Eyongetah Tabenyang Mbu | Zendy; Lydia M Besong | Zendy; Bella A Sama | Zendy; Emmanuel Orock | Zendy; Roger D. Kouyos | Zendy; Huldrych F. Günthard | Zendy; Karin J. Metzner | Zendy

Open Access

Low prevalence of transmitted HIV-1 drug resistance detected by a dried blood spot (DBS)-based next-generation sequencing (NGS) method in newly diagnosed individuals in Cameroon in the years 2015–16

Author(s) -

Herbert A Mbunkah,

Alex Marzel,

Stefan Schmutz,

Yik Lim Kok,

Osvaldo Zagordi,

Mohaned Shilaih,

Ndi N Nsanwe,

Eyongetah Tabenyang Mbu,

Lydia M Besong,

Bella A Sama,

Emmanuel Orock,

Roger D. Kouyos,

Huldrych F. Günthard,

Karin J. Metzner

Publication year - 2018

Publication title -

journal of antimicrobial chemotherapy

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.124

H-Index - 194

eISSN - 1460-2091

pISSN - 0305-7453

DOI - 10.1093/jac/dky103

Subject(s) - dried blood spot , human immunodeficiency virus (hiv) , drug resistance , medicine , dried blood , drug , dna sequencing , virology , multi drug resistant , biology , microbiology and biotechnology , pharmacology , genetics , dna , chemistry , chromatography

To determine the most recent prevalence, transmission patterns and risk factors of transmitted drug-resistance mutations (TDRMs) in Cameroon, we initiated a multicentre study monitoring HIV-1 drug resistance in newly HIV-1-diagnosed individuals using a novel next-generation sequencing (NGS) assay applicable to fingerprick dried blood spot (DBS) samples.

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