Dolutegravir-based maintenance monotherapy versus dual therapy with lamivudine: a planned 24 week analysis of the DOLAM randomized clinical trial
Author(s) -
José Luís Blanco,
Jhon Rojas,
Roger Paredes,
Eugènia Negredo,
Josep Mallolas,
María Casadellà,
Bonaventura Clotet,
José M. Gatell,
Elisa de Lazzari,
Estebán Martínez,
Alexy Inciarte,
Montserrat Laguno,
Marı́a Martı́nez-Rebollar,
Berta Torres,
Montserrat Loncà,
Amparo Tricas,
Ana Belén Rodríguez,
Pilar Callau,
Montserrat Plana,
Alberto Crespo,
S Vicente Sánchez,
Xavier Carné,
José Antonio Martínez,
Francesc Vidal
Publication year - 2018
Publication title -
journal of antimicrobial chemotherapy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.124
H-Index - 194
eISSN - 1460-2091
pISSN - 0305-7453
DOI - 10.1093/jac/dky093
Subject(s) - dolutegravir , medicine , randomized controlled trial , lamivudine , clinical trial , maintenance therapy , pharmacology , virology , viral load , human immunodeficiency virus (hiv) , antiretroviral therapy , chemotherapy , virus , hepatitis b virus
No controlled comparisons between dolutegravir/lamivudine or dolutegravir maintenance therapy have been done. We hypothesized that these options would have similar efficacy to triple ART.
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