Diversity of mutations in regulatory genes of resistance-nodulation-cell division efflux pumps in association with tigecycline resistance in Acinetobacter baumannii | Zendy

Stefanie Gerson | Zendy; Jennifer Nowak | Zendy; Esther Zander | Zendy; Julia Ertel | Zendy; Yurong Wen | Zendy; Oleg Krut | Zendy; Harald Seifert | Zendy; Paul G. Higgins | Zendy

Open Access

Diversity of mutations in regulatory genes of resistance-nodulation-cell division efflux pumps in association with tigecycline resistance in Acinetobacter baumannii

Author(s) -

Stefanie Gerson,

Jennifer Nowak,

Esther Zander,

Julia Ertel,

Yurong Wen,

Oleg Krut,

Harald Seifert,

Paul G. Higgins

Publication year - 2018

Publication title -

journal of antimicrobial chemotherapy

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.124

H-Index - 194

eISSN - 1460-2091

pISSN - 0305-7453

DOI - 10.1093/jac/dky083

Subject(s) - tigecycline , acinetobacter baumannii , efflux , biology , agar dilution , microbiology and biotechnology , gene , genetics , bacteria , antimicrobial , minimum inhibitory concentration , pseudomonas aeruginosa

To investigate the mechanisms of tigecycline resistance in isogenic Acinetobacter baumannii isolate pairs as well as 65 unique clinical A. baumannii isolates obtained during the MagicBullet clinical trial from Greece, Italy and Spain.

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