Antimicrobial activity of ellagic acid against Helicobacter pylori isolates from India and during infections in mice | Zendy

Ronita De | Zendy; Avijit Sarkar | Zendy; Prachetash Ghosh | Zendy; Mou Ganguly | Zendy; Bipul Chandra Karmakar | Zendy; Dhira Rani Saha | Zendy; Aniket Halder | Zendy; Abhijit Chowdhury | Zendy; Asish K. Mukhopadhyay | Zendy

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Antimicrobial activity of ellagic acid against Helicobacter pylori isolates from India and during infections in mice

Author(s) -

Ronita De,

Avijit Sarkar,

Prachetash Ghosh,

Mou Ganguly,

Bipul Chandra Karmakar,

Dhira Rani Saha,

Aniket Halder,

Abhijit Chowdhury,

Asish K. Mukhopadhyay

Publication year - 2018

Publication title -

journal of antimicrobial chemotherapy

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.124

H-Index - 194

eISSN - 1460-2091

pISSN - 0305-7453

DOI - 10.1093/jac/dky079

Subject(s) - ellagic acid , antimicrobial , helicobacter pylori , microbiology and biotechnology , helicobacter infections , anti infective agents , biology , helicobacter , traditional medicine , medicine , biochemistry , polyphenol , antioxidant

Because of the rise in antimicrobial resistance, an inexpensive, diet-based treatment against Helicobacter pylori infection would be of great interest. The present study was performed to assess the in vitro effects of ellagic acid against clinical H. pylori strains that were resistant to antibiotics used for therapy and also to observe the morphological structure following treatment with ellagic acid. The effectiveness of ellagic acid in eradicating H. pylori infection in a murine (C57BL/6) infection model, one of the standard inbred mouse lines often used for experimental infection, was also assessed.

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