Pharmacokinetics of piperacillin in critically ill patients with acute kidney injury receiving sustained low-efficiency diafiltration | Zendy

Mahipal Sinnollareddy | Zendy; Michael S. Roberts | Zendy; Jeffrey Lipman | Zendy; Sandra Peake | Zendy; Jason A. Roberts | Zendy

Open Access

Pharmacokinetics of piperacillin in critically ill patients with acute kidney injury receiving sustained low-efficiency diafiltration

Author(s) -

Mahipal Sinnollareddy,

Michael S. Roberts,

Jeffrey Lipman,

Sandra Peake,

Jason A. Roberts

Publication year - 2018

Publication title -

journal of antimicrobial chemotherapy

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.124

H-Index - 194

eISSN - 1460-2091

pISSN - 0305-7453

DOI - 10.1093/jac/dky057

Subject(s) - piperacillin , medicine , pharmacokinetics , dosing , renal replacement therapy , piperacillin/tazobactam , anesthesia , area under the curve , clearance , tazobactam , renal function , urology , surgery , pseudomonas aeruginosa , biology , genetics , bacteria

Piperacillin is a β-lactam penicillin antibiotic commonly used for the empirical therapy of sepsis and other hospital-acquired infections. However, knowledge regarding the effect of sustained low-efficiency diafiltration (SLED-f), a technique increasingly being used in ICUs, on piperacillin pharmacokinetics (PK) and dosing in critically ill patients is lacking.

The content you want is available to Zendy users.

Already have an account? Click here to sign in.

Having issues? You can contact us here

Accelerating Research