Pharmacodynamics and cellular accumulation of amphotericin B and miltefosine in Leishmania donovani-infected primary macrophages | Zendy

Andrew A. Voak | Zendy; Joseph F. Standing | Zendy; Nuno Sepúlveda | Zendy; Andy Harris | Zendy; Simon L. Croft | Zendy; Karin Seifert | Zendy

Open Access

Pharmacodynamics and cellular accumulation of amphotericin B and miltefosine in Leishmania donovani-infected primary macrophages

Author(s) -

Andrew A. Voak,

Joseph F. Standing,

Nuno Sepúlveda,

Andy Harris,

Simon L. Croft,

Karin Seifert

Publication year - 2018

Publication title -

journal of antimicrobial chemotherapy

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.124

H-Index - 194

eISSN - 1460-2091

pISSN - 0305-7453

DOI - 10.1093/jac/dky014

Subject(s) - miltefosine , amastigote , leishmania donovani , pharmacology , amphotericin b , leishmania , biology , extracellular , in vivo , microbiology and biotechnology , visceral leishmaniasis , immunology , leishmaniasis , biochemistry , antifungal , parasite hosting , world wide web , computer science

We examined the in vitro pharmacodynamics and cellular accumulation of the standard anti-leishmanial drugs amphotericin B and miltefosine in intracellular Leishmania donovani amastigote-macrophage drug assays.

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