Development of a dosing nomogram for continuous-infusion meropenem in critically ill patients based on a validated population pharmacokinetic model | Zendy

Iris K. Minichmayr | Zendy; Jason A. Roberts | Zendy; Otto Frey | Zendy; Anka C. Roehr | Zendy; Charlotte Kloft | Zendy; Alexander Brinkmann | Zendy

Open Access

Development of a dosing nomogram for continuous-infusion meropenem in critically ill patients based on a validated population pharmacokinetic model

Author(s) -

Iris K. Minichmayr,

Jason A. Roberts,

Otto Frey,

Anka C. Roehr,

Charlotte Kloft,

Alexander Brinkmann

Publication year - 2018

Publication title -

journal of antimicrobial chemotherapy

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.124

H-Index - 194

eISSN - 1460-2091

pISSN - 0305-7453

DOI - 10.1093/jac/dkx526

Subject(s) - meropenem , dosing , pharmacokinetics , medicine , nomogram , renal function , nonmem , population , therapeutic drug monitoring , kidney disease , creatinine , pharmacology , intensive care medicine , urology , antibiotics , chemistry , environmental health , antibiotic resistance , biochemistry

Optimal antibiotic exposure is a vital but challenging prerequisite for achieving clinical success in ICU patients.

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