Population pharmacokinetics and probability of target attainment of ertapenem administered by subcutaneous or intravenous route in patients with bone and joint infection | Zendy

Sylvain Goutelle | Zendy; Florent Valour | Zendy; MarieClaude Gagnieu | Zendy; Frédéric Laurent | Zendy; Christian Chidiac | Zendy; Tristan Ferry | Zendy; Thomas Perpoint | Zendy; A. Boibieux | Zendy; F. Biron | Zendy; Patrick Miailhes | Zendy; Florence Ader | Zendy; Agathe Becker | Zendy; Sandrine Roux | Zendy; Claire Triffault-Fillit | Zendy; Fatiha Daoud | Zendy; Johanna Lippman | Zendy; E. Braun | Zendy; Yves Gillet | Zendy; Laure Hees | Zendy; Sébastien Lustig | Zendy; Elvire Servıen | Zendy; Yannick Herry | Zendy; Romain Gaillard | Zendy; Antoine Schneider | Zendy; Michel-Henry Fessy | Zendy; Anthony Viste | Zendy; Philippe Chaudier | Zendy; Romain Desmarchelier | Zendy; Tanguy Mouton | Zendy; Cyril Courtin | Zendy; Lucie Louboutin | Zendy; Sébastien Martres | Zendy; Franck Trouillet | Zendy; Cédric Barrey | Zendy; Francesco Signorelli | Zendy; Emmanuel Jouanneau | Zendy; Timothée Jacquesson | Zendy; A. Mojallal | Zendy; Fabien Boucher | Zendy; Hristo Shipkov | Zendy; Mehdi Ismail | Zendy; Joseph Château | Zendy; Frédéric Aubrun | Zendy; I. Bobineau | Zendy; Caroline Macabéo | Zendy; François Vandenesch | Zendy; Jean-Philippe Rasigade | Zendy; Céline Dupieux | Zendy; Fabien Craighero | Zendy; Loïc Boussel | Zendy; JeanBaptiste Pialat | Zendy; Isabelle Morelec | Zendy; M. Janier | Zendy; Francesco Giammarile | Zendy; Michel Tod | Zendy; Solweig Gerbier-Colomban | Zendy; Thomas Bénet | Zendy; Eugénie Mabrut | Zendy

Open Access

Population pharmacokinetics and probability of target attainment of ertapenem administered by subcutaneous or intravenous route in patients with bone and joint infection

Author(s) -

Sylvain Goutelle,

Florent Valour,

MarieClaude Gagnieu,

Frédéric Laurent,

Christian Chidiac,

Tristan Ferry,

Thomas Perpoint,

A. Boibieux,

F. Biron,

Patrick Miailhes,

Florence Ader,

Agathe Becker,

Sandrine Roux,

Claire Triffault-Fillit,

Fatiha Daoud,

Johanna Lippman,

E. Braun,

Yves Gillet,

Laure Hees,

Sébastien Lustig,

Elvire Servıen,

Yannick Herry,

Romain Gaillard,

Antoine Schneider,

Michel-Henry Fessy,

Anthony Viste,

Philippe Chaudier,

Romain Desmarchelier,

Tanguy Mouton,

Cyril Courtin,

Lucie Louboutin,

Sébastien Martres,

Franck Trouillet,

Cédric Barrey,

Francesco Signorelli,

Emmanuel Jouanneau,

Timothée Jacquesson,

A. Mojallal,

Fabien Boucher,

Hristo Shipkov,

Mehdi Ismail,

Joseph Château,

Frédéric Aubrun,

I. Bobineau,

Caroline Macabéo,

François Vandenesch,

Jean-Philippe Rasigade,

Céline Dupieux,

Fabien Craighero,

Loïc Boussel,

JeanBaptiste Pialat,

Isabelle Morelec,

M. Janier,

Francesco Giammarile,

Michel Tod,

Solweig Gerbier-Colomban,

Thomas Bénet,

Eugénie Mabrut

Publication year - 2017

Publication title -

journal of antimicrobial chemotherapy

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.124

H-Index - 194

eISSN - 1460-2091

pISSN - 0305-7453

DOI - 10.1093/jac/dkx477

Subject(s) - ertapenem , pharmacokinetics , medicine , population , dosing , pharmacodynamics , urology , renal function , pharmacology , chemistry , antibiotics , meropenem , biochemistry , environmental health , antibiotic resistance

Ertapenem is a therapeutic option in patients with Gram-negative bone and joint infection (BJI). The subcutaneous (sc) route of administration is convenient in the outpatient setting and has shown favourable pharmacokinetics (PK), but available data on ertapenem are limited.

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