Pharmacokinetics of darunavir/cobicistat and etravirine alone and co-administered in HIV-infected patients
Author(s) -
José Moltó,
Adrián Curran,
Cristina Miranda,
Elizabeth Challenger,
José Ramón Santos,
Esteban Ribera,
Saye Khoo,
Marta Valle,
Bonaventura Clotet
Publication year - 2017
Publication title -
journal of antimicrobial chemotherapy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.124
H-Index - 194
eISSN - 1460-2091
pISSN - 0305-7453
DOI - 10.1093/jac/dkx459
Subject(s) - etravirine , darunavir , cobicistat , ritonavir , cmax , pharmacokinetics , pharmacology , medicine , cmin , chemistry , virology , viral load , human immunodeficiency virus (hiv) , antiretroviral therapy
To determine the effect of etravirine on the pharmacokinetics of darunavir/cobicistat and vice versa. Safety and tolerability of this combination were also evaluated.
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