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Comparative analysis of neutropenia in patients receiving prolonged treatment with ceftaroline
Author(s) -
R. Brigg Turner,
Dorinda Wilson,
Henry Saedi-Kwon,
Eric L. Chang,
Regina Won,
Dominic Chan,
Jacqueline Schwartz
Publication year - 2017
Publication title -
journal of antimicrobial chemotherapy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.124
H-Index - 194
eISSN - 1460-2091
pISSN - 0305-7453
DOI - 10.1093/jac/dkx452
Subject(s) - medicine , neutropenia , daptomycin , incidence (geometry) , propensity score matching , antibacterial agent , nafcillin , vancomycin , absolute neutrophil count , antibiotics , febrile neutropenia , surgery , staphylococcus aureus , chemotherapy , physics , microbiology and biotechnology , penicillin , biology , bacteria , optics , genetics
Ceftaroline is often used in durations greater than that studied in clinical trials. Several retrospective, non-comparative studies have suggested a higher than anticipated incidence of neutropenia in patients receiving prolonged treatment with ceftaroline. We sought to determine if ceftaroline was associated with neutropenia by comparing the incidence with ceftaroline treatment with treatment with several comparative antibiotics.

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