Tolerability profile of the current antifungal armoury | Zendy

Ahmad Mourad | Zendy; John R. Perfect | Zendy

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Tolerability profile of the current antifungal armoury

Author(s) -

Ahmad Mourad,

John R. Perfect

Publication year - 2017

Publication title -

journal of antimicrobial chemotherapy

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.124

H-Index - 194

eISSN - 1460-2091

pISSN - 0305-7453

DOI - 10.1093/jac/dkx446

Subject(s) - tolerability , antifungal , medicine , antifungal drugs , current (fluid) , microbiology and biotechnology , biology , dermatology , adverse effect , electrical engineering , engineering

The tolerability of available antifungal agents is essential to the final outcome of the management of invasive mycoses. There are limited classes of antifungal agents for use, and they can have serious direct toxicities and/or drug-drug interactions. In this review, we examine the common toxicities noted for antifungal agents and attempt to both identify the issues around the adverse events and provide clinical context for their occurrence in these fragile patients.

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