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Activity of ceftazidime/avibactam against problem Enterobacteriaceae and Pseudomonas aeruginosa in the UK, 2015–16
Author(s) -
David M. Livermore,
Danièle Meunier,
Katie L. Hopkins,
Michel Doumith,
Robert L. Hill,
Rachel Pike,
Peter Staves,
Neil Woodford
Publication year - 2017
Publication title -
journal of antimicrobial chemotherapy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.124
H-Index - 194
eISSN - 1460-2091
pISSN - 0305-7453
DOI - 10.1093/jac/dkx438
Subject(s) - ceftazidime , ceftazidime/avibactam , avibactam , cephalosporin , microbiology and biotechnology , klebsiella pneumoniae , pseudomonas aeruginosa , enterobacteriaceae , biology , ertapenem , acinetobacter baumannii , agar dilution , efflux , antibiotic resistance , antibiotics , meropenem , minimum inhibitory concentration , escherichia coli , bacteria , gene , genetics
Ceftazidime/avibactam combines an established oxyimino-cephalosporin with the first diazabicyclooctane β-lactamase inhibitor to enter clinical use. We reviewed its activity against Gram-negative isolates, predominantly from the UK, referred for resistance investigation in the first year of routine testing, beginning in July 2015.

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