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Pharmacokinetics/pharmacodynamics of systemically administered polymyxin B against Klebsiella pneumoniae in mouse thigh and lung infection models
Author(s) -
Cornelia B. Landersdorfer,
Jiping Wang,
Veronika Wirth,
Ke Chen,
Keith S. Kaye,
Brian T. Tsuji,
Jian Li,
Roger L. Nation
Publication year - 2017
Publication title -
journal of antimicrobial chemotherapy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.124
H-Index - 194
eISSN - 1460-2091
pISSN - 0305-7453
DOI - 10.1093/jac/dkx409
Subject(s) - pharmacokinetics , polymyxin b , polymyxin , klebsiella pneumoniae , colistin , medicine , pharmacodynamics , pharmacology , antibacterial agent , antibiotics , population , minimum inhibitory concentration , microbiology and biotechnology , chemistry , biology , escherichia coli , biochemistry , environmental health , gene
The pharmacokinetic/pharmacodynamic (PK/PD) relationship for polymyxin B against Klebsiella pneumoniae infections is not known.

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