Activity of colistin alone or in combination with rifampicin or meropenem in a carbapenem-resistant bioluminescent Pseudomonas aeruginosa intraperitoneal murine infection model
Author(s) -
Yun Cai,
Deqing Yang,
Jin Wang,
Rui Wang
Publication year - 2017
Publication title -
journal of antimicrobial chemotherapy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.124
H-Index - 194
eISSN - 1460-2091
pISSN - 0305-7453
DOI - 10.1093/jac/dkx399
Subject(s) - meropenem , colistin , rifampicin , ex vivo , pharmacology , in vivo , pseudomonas aeruginosa , microbiology and biotechnology , antibiotics , carbapenem , medicine , combination therapy , biology , bacteria , antibiotic resistance , genetics
Carbapenem-resistant Pseudomonas aeruginosa (CRPA) infections represent a major therapeutic problem and combination therapy may be the chemotherapeutic option.
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