Distribution of putative virulence markers in Enterococcus faecium: towards a safety profile review | Zendy

Ana R. Freitas | Zendy; Ana P. Tedim | Zendy; Carla Novais | Zendy; Teresa M. Coque | Zendy; Luı́sa Peixe | Zendy

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Distribution of putative virulence markers in Enterococcus faecium: towards a safety profile review

Author(s) -

Ana R. Freitas,

Ana P. Tedim,

Carla Novais,

Teresa M. Coque,

Luı́sa Peixe

Publication year - 2017

Publication title -

journal of antimicrobial chemotherapy

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.124

H-Index - 194

eISSN - 1460-2091

pISSN - 0305-7453

DOI - 10.1093/jac/dkx387

Subject(s) - enterococcus faecium , virulence , enterococcus , microbiology and biotechnology , biology , genetics , antibiotics , gene

The criteria for identification of Enterococcus faecium (Efm) with the ability to cause human infections are currently being debated by the European Food Safety Authority (EFSA). Strains that have an MIC of ampicillin of ≤ 2 mg/L and lack IS16/esp/hyl genes should be regarded as safe for use as feed additives in animal nutrition, despite the lack of knowledge about putative virulence marker (PVM) distribution in community Efm. We analysed the distribution of major PVM and ampicillin phenotypes in large Efm collections to investigate further the safety of strains from a public health perspective.

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