z-logo
open-access-imgOpen Access
Analysis of Clostridium difficile biofilms: imaging and antimicrobial treatment
Author(s) -
Garth A. James,
Laurent Chesnel,
Laura Boegli,
Elinor deLancey Pulcini,
Steve Fisher,
Philip S. Stewart
Publication year - 2017
Publication title -
journal of antimicrobial chemotherapy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.124
H-Index - 194
eISSN - 1460-2091
pISSN - 0305-7453
DOI - 10.1093/jac/dkx353
Subject(s) - fidaxomicin , microbiology and biotechnology , metronidazole , clostridium difficile , biofilm , vancomycin , antibiotics , antimicrobial , spore , biology , bacteria , staphylococcus aureus , genetics
Clostridium difficile, a spore-forming Gram-positive anaerobic bacillus, is the most common causative agent of healthcare-associated diarrhoea. Formation of biofilms may protect C. difficile against antibiotics, potentially leading to treatment failure. Furthermore, bacterial spores or vegetative cells may linger in biofilms in the gut causing C. difficile infection recurrence.

The content you want is available to Zendy users.

Already have an account? Click here to sign in.
Having issues? You can contact us here
Accelerating Research

Address

John Eccles House
Robert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom