A comparison of levofloxacin and oral third-generation cephalosporins as antibacterial prophylaxis in acute leukaemia patients during chemotherapy-induced neutropenia | Zendy

Kristyn E Yemm | Zendy; Jason N. Barreto | Zendy; Kristin C. Mara | Zendy; Ross Dierkhising | Zendy; Naseema Gangat | Zendy; Pritish K. Tosh | Zendy

Open Access

A comparison of levofloxacin and oral third-generation cephalosporins as antibacterial prophylaxis in acute leukaemia patients during chemotherapy-induced neutropenia

Author(s) -

Kristyn E Yemm,

Jason N. Barreto,

Kristin C. Mara,

Ross Dierkhising,

Naseema Gangat,

Pritish K. Tosh

Publication year - 2017

Publication title -

journal of antimicrobial chemotherapy

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.124

H-Index - 194

eISSN - 1460-2091

pISSN - 0305-7453

DOI - 10.1093/jac/dkx338

Subject(s) - medicine , levofloxacin , cephalosporin , neutropenia , chemotherapy , antibacterial agent , febrile neutropenia , antibiotics , microbiology and biotechnology , biology

There is demonstrated benefit with fluoroquinolones as infection prophylaxis in neutropenic patients; however, side effects, drug interactions and increasing resistance necessitate investigation of alternative therapies.

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