Open AccessAmpC β-lactamase induction by avibactam and relebactam
Author(s) -
David M. Livermore,
Dorota Jamrozy,
Shazad Mushtaq,
Wright W. Nichols,
Katherine Young,
Neil Woodford
Publication year - 2017
Publication title -
journal of antimicrobial chemotherapy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.124
H-Index - 194
eISSN - 1460-2091
pISSN - 0305-7453
DOI - 10.1093/jac/dkx298
Subject(s) - avibactam , ceftazidime/avibactam , medicine , microbiology and biotechnology , biology , enterobacteriaceae , escherichia coli , biochemistry , gene
Diazabicyclooctanes, e.g. avibactam and relebactam, are a new class of β-lactamase inhibitors. Their spectrum includes AmpC enzymes, but it is important to understand whether they also induce these enzymes.
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