A randomized controlled trial of probiotics for Clostridium difficile infection in adults (PICO) | Zendy

Anna K. Barker | Zendy; Megan Duster | Zendy; Susan Valentine | Zendy; Timothy Hess | Zendy; Laurie ArchbaldPan | Zendy; Richard L. Guerrant | Zendy; Nasia Safdar | Zendy

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A randomized controlled trial of probiotics for Clostridium difficile infection in adults (PICO)

Author(s) -

Anna K. Barker,

Megan Duster,

Susan Valentine,

Timothy Hess,

Laurie ArchbaldPan,

Richard L. Guerrant,

Nasia Safdar

Publication year - 2017

Publication title -

journal of antimicrobial chemotherapy

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.124

H-Index - 194

eISSN - 1460-2091

pISSN - 0305-7453

DOI - 10.1093/jac/dkx254

Subject(s) - clostridium difficile , microbiology and biotechnology , clostridium infections , medicine , randomized controlled trial , c difficile , antibiotics , biology

Clostridium difficile is the most common cause of hospital-acquired infections, responsible for >450000 infections annually in the USA. Probiotics provide a promising, well-tolerated adjunct therapy to standard C. difficile infection (CDI) treatment regimens, but there is a paucity of data regarding their effectiveness for the treatment of an initial CDI.

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