Rates of virological suppression and drug resistance in adult HIV-1-positive patients attending primary healthcare facilities in KwaZulu-Natal, South Africa
Author(s) -
Gillian Hunt,
E. Kainne Dokubo,
Simbarashe Takuva,
Túlio de Oliveira,
Johanna Ledwaba,
Nomathemba Dube,
Pravi Moodley,
Jennifer Sabatier,
Varough Deyde,
Lynn Morris,
Elliot Raizes
Publication year - 2017
Publication title -
journal of antimicrobial chemotherapy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.124
H-Index - 194
eISSN - 1460-2091
pISSN - 0305-7453
DOI - 10.1093/jac/dkx252
Subject(s) - drug resistance , medicine , human immunodeficiency virus (hiv) , hiv drug resistance , drug , primary health care , health care , virology , antiretroviral therapy , viral load , environmental health , pharmacology , biology , population , microbiology and biotechnology , economics , economic growth
KwaZulu-Natal (KZN) Province in South Africa has the highest HIV disease burden in the country, with an estimated population prevalence of 24.7%. A pilot sentinel surveillance project was undertaken in KZN to classify the proportion of adult patients failing first-line ART and to describe the patterns of drug resistance mutations (DRMs) in patients with virological failure (VF).
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