Penetration of linezolid into synovial fluid and muscle tissue after elective arthroscopy | Zendy

Richard Schwameis | Zendy; Stefanie Syré | Zendy; Kambiz Sarahrudi | Zendy; A.L. Appelt | Zendy; Daniela Marhofer | Zendy; Daniela Burau | Zendy; Charlotte Kloft | Zendy; Markus Zeitlinger | Zendy

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Penetration of linezolid into synovial fluid and muscle tissue after elective arthroscopy

Author(s) -

Richard Schwameis,

Stefanie Syré,

Kambiz Sarahrudi,

A.L. Appelt,

Daniela Marhofer,

Daniela Burau,

Charlotte Kloft,

Markus Zeitlinger

Publication year - 2017

Publication title -

journal of antimicrobial chemotherapy

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.124

H-Index - 194

eISSN - 1460-2091

pISSN - 0305-7453

DOI - 10.1093/jac/dkx219

Subject(s) - penetration (warfare) , medicine , arthroscopy , linezolid , synovial fluid , surgery , pathology , staphylococcus aureus , vancomycin , biology , bacteria , operations research , alternative medicine , genetics , osteoarthritis , engineering

Penetration of antibiotics into synovial fluid is crucial to combat septic arthritis efficiently. Since linezolid may be used for treatment of septic arthritis when methicillin-resistant bacterial strains are suspected, we investigated its target-site concentrations in synovial fluid.

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