Monitoring microevolution of OXA-48-producing Klebsiella pneumoniae ST147 in a hospital setting by SMRT sequencing | Zendy

Andreas E. Zautner | Zendy; Boyke Bunk | Zendy; Yvonne Pfeifer | Zendy; Cathrin Spröer | Zendy; Utz Reichard | Zendy; Helmut Eiffert | Zendy; Simone Scheithauer | Zendy; Uwe Groß | Zendy; Jörg Overmann | Zendy; Wolfgang Bohne | Zendy

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Monitoring microevolution of OXA-48-producing Klebsiella pneumoniae ST147 in a hospital setting by SMRT sequencing

Author(s) -

Andreas E. Zautner,

Boyke Bunk,

Yvonne Pfeifer,

Cathrin Spröer,

Utz Reichard,

Helmut Eiffert,

Simone Scheithauer,

Uwe Groß,

Jörg Overmann,

Wolfgang Bohne

Publication year - 2017

Publication title -

journal of antimicrobial chemotherapy

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.124

H-Index - 194

eISSN - 1460-2091

pISSN - 0305-7453

DOI - 10.1093/jac/dkx216

Subject(s) - klebsiella pneumoniae , microevolution , microbiology and biotechnology , biology , medicine , genetics , escherichia coli , gene , environmental health , population

Carbapenemase-producing Klebsiella pneumoniae pose an increasing risk for healthcare facilities worldwide. A continuous monitoring of ST distribution and its association with resistance and virulence genes is required for early detection of successful K. pneumoniae lineages. In this study, we used WGS to characterize MDR blaOXA-48-positive K. pneumoniae isolated from inpatients at the University Medical Center Göttingen, Germany, between March 2013 and August 2014.

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