Genetic alterations responsible for reduced susceptibility to vancomycin in community-associated MRSA strains of ST72 | Zendy

Jin Yang Baek | Zendy; Doo Ryeon Chung | Zendy; Kwan Soo Ko | Zendy; Kim Ys | Zendy; SooJin Yang | Zendy; CheolIn Kang | Zendy; Kyong Ran Peck | Zendy; JaeHoon Song | Zendy

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Genetic alterations responsible for reduced susceptibility to vancomycin in community-associated MRSA strains of ST72

Author(s) -

Jin Yang Baek,

Doo Ryeon Chung,

Kwan Soo Ko,

Kim Ys,

SooJin Yang,

CheolIn Kang,

Kyong Ran Peck,

JaeHoon Song

Publication year - 2017

Publication title -

journal of antimicrobial chemotherapy

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.124

H-Index - 194

eISSN - 1460-2091

pISSN - 0305-7453

DOI - 10.1093/jac/dkx175

Subject(s) - vancomycin , rpob , microbiology and biotechnology , staphylococcus aureus , genotype , rifampicin , antibiotics , biology , methicillin resistant staphylococcus aureus , population , mutation , genotype phenotype distinction , genetics , gene , medicine , bacteria , 16s ribosomal rna , environmental health

We previously reported the first case of vancomycin treatment failure due to development of vancomycin-intermediate resistance in a patient with an MRSA of ST72, a community genotype in Korea. We investigated two isogenic MRSA strains from this patient, who experienced treatment failure with vancomycin and rifampicin.

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