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FRI-2 carbapenemase-producing Enterobacter cloacae complex in the UK
Author(s) -
Danièle Meunier,
Jacqueline Findlay,
Michel Doumith,
Daniel Godoy,
Claire Perry,
Rachel Pike,
Firza Alexander Gronthoud,
Theresa Shryane,
Laurent Poirel,
William Welfare,
Neil Woodford,
Katie L. Hopkins
Publication year - 2017
Publication title -
journal of antimicrobial chemotherapy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.124
H-Index - 194
eISSN - 1460-2091
pISSN - 0305-7453
DOI - 10.1093/jac/dkx173
Subject(s) - enterobacter cloacae , ertapenem , meropenem , microbiology and biotechnology , carbapenem , imipenem , biology , klebsiella pneumoniae , tazobactam , agar dilution , piperacillin , gene , antimicrobial , pseudomonas aeruginosa , antibiotic resistance , bacteria , minimum inhibitory concentration , genetics , antibiotics , escherichia coli
Detection of rarer carbapenemases is challenging, as it requires molecular assays with comprehensive coverage or the use of phenotypic methods for the detection of carbapenemase activity. We describe a new class A carbapenemase, FRI-2, in an Enterobacter cloacae complex isolate following implementation of an in-house multiplex PCR for the detection of 'rare' class A carbapenemases.

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