Prevention of TB using rifampicin plus isoniazid reduces nevirapine concentrations in HIV-exposed infants | Zendy

Helen McIlleron | Zendy; Paolo Denti | Zendy; Silvia Cohn | Zendy; Fildah Mashabela | Zendy; Jennifer Hoffmann | Zendy; Saba Shembe | Zendy; Regina Msandiwa | Zendy; Lubbe Wiesner | Zendy; Sithembiso Velaphi | Zendy; Sanjay G. Lala | Zendy; Richard E. Chaisson | Zendy; Neil Martinson | Zendy; Kelly E. Dooley | Zendy

AI Assistant Blog Pricing

Home ZAIA Blog

Open Access

Prevention of TB using rifampicin plus isoniazid reduces nevirapine concentrations in HIV-exposed infants

Author(s) -

Helen McIlleron,

Paolo Denti,

Silvia Cohn,

Fildah Mashabela,

Jennifer Hoffmann,

Saba Shembe,

Regina Msandiwa,

Lubbe Wiesner,

Sithembiso Velaphi,

Sanjay G. Lala,

Richard E. Chaisson,

Neil Martinson,

Kelly E. Dooley

Publication year - 2017

Publication title -

journal of antimicrobial chemotherapy

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.124

H-Index - 194

eISSN - 1460-2091

pISSN - 0305-7453

DOI - 10.1093/jac/dkx112

Subject(s) - nevirapine , medicine , rifampicin , isoniazid , pediatrics , concomitant , breastfeeding , tuberculosis , antiretroviral therapy , human immunodeficiency virus (hiv) , immunology , viral load , pathology

Newborns of HIV-infected mothers are given daily doses of nevirapine to prevent HIV-1 acquisition. Infants born to mothers with TB should also receive TB preventive therapy. TB preventive regimens include isoniazid for 6 months or rifampicin plus isoniazid for 3 months (RH preventive therapy). The effect of concomitant RH preventive therapy on nevirapine concentrations in infants is unknown.

The content you want is available to Zendy users.

Already have an account? Click here to sign in.

Having issues? You can contact us here

Accelerating Research