Overexpression of antibiotic resistance genes in hospital effluents over time | Zendy

Will Rowe | Zendy; Craig BakerAustin | Zendy; David W. Verner–Jeffreys | Zendy; Jim J. Ryan | Zendy; Christianne Micallef | Zendy; Duncan J. Maskell | Zendy; GR Pearce | Zendy

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Overexpression of antibiotic resistance genes in hospital effluents over time

Author(s) -

Will Rowe,

Craig BakerAustin,

David W. Verner–Jeffreys,

Jim J. Ryan,

Christianne Micallef,

Duncan J. Maskell,

GR Pearce

Publication year - 2017

Publication title -

journal of antimicrobial chemotherapy

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.124

H-Index - 194

eISSN - 1460-2091

pISSN - 0305-7453

DOI - 10.1093/jac/dkx017

Subject(s) - antibiotics , gene , antibiotic resistance , microbiology and biotechnology , biology , medicine , genetics

Effluents contain a diverse abundance of antibiotic resistance genes that augment the resistome of receiving aquatic environments. However, uncertainty remains regarding their temporal persistence, transcription and response to anthropogenic factors, such as antibiotic usage. We present a spatiotemporal study within a river catchment (River Cam, UK) that aims to determine the contribution of antibiotic resistance gene-containing effluents originating from sites of varying antibiotic usage to the receiving environment.

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