Effect of rifampicin and efavirenz on moxifloxacin concentrations when co-administered in patients with drug-susceptible TB
Author(s) -
Anushka Naidoo,
Maxwell Chirehwa,
Helen McIlleron,
Kogieleum Naidoo,
Sabiha Y. Essack,
hlanhla YendeZuma,
Eddy Kimba-Phongi,
John Adamson,
Katya Govender,
Nesri Padayatchi,
Paolo Denti
Publication year - 2017
Publication title -
journal of antimicrobial chemotherapy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.124
H-Index - 194
eISSN - 1460-2091
pISSN - 0305-7453
DOI - 10.1093/jac/dkx004
Subject(s) - moxifloxacin , rifampicin , efavirenz , pharmacokinetics , medicine , pyrazinamide , pharmacology , isoniazid , regimen , antibacterial agent , antibiotics , tuberculosis , human immunodeficiency virus (hiv) , chemistry , antiretroviral therapy , viral load , immunology , biochemistry , pathology
We compared the pharmacokinetics of moxifloxacin during rifampicin co-treatment or when dosed alone in African patients with drug-susceptible recurrent TB.
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