Potentiation of ceftazidime by avibactam against β-lactam-resistantPseudomonas aeruginosain anin vitroinfection model | Zendy

Sherwin K. B. Sy | Zendy; Luning Zhuang | Zendy; MarieEve Beaudoin | Zendy; Philipp Kircher | Zendy; Maria Alice Maciel Tabosa | Zendy; Noely C. T. Cavalcanti | Zendy; Christian Grunwitz | Zendy; Sebastian Pieper | Zendy; Virna Schuck | Zendy; Wright W. Nichols | Zendy; Hartmut Derendorf | Zendy

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Potentiation of ceftazidime by avibactam against β-lactam-resistantPseudomonas aeruginosain anin vitroinfection model

Author(s) -

Sherwin K. B. Sy,

Luning Zhuang,

MarieEve Beaudoin,

Philipp Kircher,

Maria Alice Maciel Tabosa,

Noely C. T. Cavalcanti,

Christian Grunwitz,

Sebastian Pieper,

Virna Schuck,

Wright W. Nichols,

Hartmut Derendorf

Publication year - 2016

Publication title -

journal of antimicrobial chemotherapy

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.124

H-Index - 194

eISSN - 1460-2091

pISSN - 0305-7453

DOI - 10.1093/jac/dkw535

Subject(s) - ceftazidime/avibactam , avibactam , ceftazidime , microbiology and biotechnology , pseudomonas aeruginosa , tazobactam , pharmacodynamics , pharmacology , piperacillin , medicine , chemistry , biology , pharmacokinetics , bacteria , genetics

This study evaluated the in vitro pharmacodynamics of combinations of ceftazidime and the non-β-lactam β-lactamase inhibitor, avibactam, against ceftazidime-, piperacillin/tazobactam- and meropenem-multiresistant Pseudomonas aeruginosa by a quantitative time-kill method.

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