Impact of obesity on antiretroviral pharmacokinetics and immuno-virological response in HIV-infected patients: a case–control study
Author(s) -
Vincent Madelain,
Minh Patrick Lê,
Karen Champenois,
Charlotte Charpentier,
Roland Landman,
Véronique Joly,
Patrick Yéni,
Diane Descamps,
Yazdan Yazdanpanah,
Gilles Peytavin
Publication year - 2016
Publication title -
journal of antimicrobial chemotherapy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.124
H-Index - 194
eISSN - 1460-2091
pISSN - 0305-7453
DOI - 10.1093/jac/dkw527
Subject(s) - pharmacokinetics , medicine , antiretroviral drug , human immunodeficiency virus (hiv) , obesity , antiretroviral therapy , virology , viral load , immunology
Obesity has high prevalence among HIV-infected patients. Increased adipose tissue mass affects the pharmacokinetics of numerous drugs, but few data are available for antiretroviral drugs.
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